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Ibrutinib dimer；依魯替尼二聚體Ibrutinib dimer (2024/8/29)
簡介：ibrutinib dimer is an impurity of ibrutinib. iibrutinib dimer is a dimer of ibrutinib. ibrutinib is an irreversible btk inhibitor (ic50: 0.5 nm).
Ibrutinib-d5；化合物 T11601PCI-32765 D5|||Ibrutinib D5；PCI-32765 D5|||Ibrutinib D5 (2024/8/29)
簡介：ibrutinib d5 is a deuterium-labeled ibrutinib. ibrutinib is an irreversible btk inhibitor.
IBR2；化合物IBR2Isoquinoline；Isoquinoline (2024/8/29)
簡介：ibr2 (isoquinoline) is a potent and specific rad51 inhibitor known for its ability to suppress rad51-mediated dna double-strand break repair. by interfering with rad51 multimerization, accelerating proteasome-mediated rad51 protein degradation, inhibiting cancer cell growth, and inducing apoptosis, ibr2 has proved to be an effective compound in these aspects.
Fusidic acid；夫西地酸Fusidine；Fusidine|||夫西地酸 (2024/8/29)
簡介：fusidic acid (fusidine) is an antibiotic isolated from the fermentation broth of fusidium coccineum.
Ibiglustat (L-Malic acid)；化合物Ibiglustat (L馬來酸)Ibiglustat L-Malic acid|||GZ402671 (L-Malic acid)|||Ve (2024/8/29)
簡介：ibiglustat (l-malic acid) (ibiglustat l-malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. ibiglustat (l-malic acid) can be used in studies about pd parkinson’s disease, srt in fabry’s and gaucher’s.
IAXO-102；化合物IAXO-102IAXO-102 (2024/8/29)
簡介：iaxo-102 is a tlr4 antagonist that negatively regulates tlr4 signaling. it inhibits mapk and p65 nf-κb phosphorylation and expression of tlr4 dependent proinflammatory protein. iaxo-102 also prevents experimental abdominal aortic aneurysm development.
IACS-9571 Hydrochloride (1800477-30-8 free base)；化合物 T11597LIACS-9571 Hydrochloride|||ASIS-P040 Hydr (2024/8/29)
簡介：iacs-9571 hydrochloride is a selective and potent inhibitor of trim24 and brpf1, (ic50: 8 nm for trim24; kds: 31 nm and 14 nm for trim24 and brpf1).
IACS-9571；化合物 T11597ASIS-P040；ASIS-P040 (2024/8/29)
簡介：iacs-9571 is a selective and potent inhibitor of trim24 and brpf1, (ic50: 8 nm for trim24; kds: 31 nm and 14 nm for trim24 and brpf1).
IACS-8803；化合物 T11596IACS-8803 (2024/8/29)
簡介：iacs-8803 is a potent cyclic dinucleotide sting agonist that exhibits strong systemic antitumor efficacy.
IACS-8779；化合物 T11595IACS-8779 (2024/8/29)
簡介：iacs-8779 is a potent sting agonist that efficiently stimulates interferon gene activity and exhibits strong systemic antitumor effects.
I2906；化合物 T11594I2906 (2024/8/29)
簡介：i2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis.
I-OMe-Tyrphostin AG 538；化合物T11593I-OMe-AG 538；I-OMe-AG 538 (2024/8/29)
簡介：i-ome-tyrphostin ag 538 is a specific igf-1r inhibitor and atp-competitive inhibitor of pi5p4kα (ic50: 1 ?m).i-ome-tyrphostin ag 538 inhibits igf-1r-mediated signaling and exhibits preferential cytotoxicity to nutrient-deficient panc1 cells.
Hydroxyzine D8；化合物 T11592Hydroxyzine D8 (2024/8/29)
簡介：hydroxyzine d8, a deuterium-labeled version of hydroxyzine, acts as a histamine h1-receptor antagonist.
Hydroxyzine D4羥嗪 D4羥嗪 D4 (2024/8/29)
簡介：hydroxyzine d4 is a deuterium-labeled variation of hydroxyzine, a chemical compound known for its anticholinergic, anxiolytic, and analgesic properties. it is classified as a heterocyclic histamine h1-receptor antagonist.
(-)-Hydroxycitric acid；(-)-羥基檸檬酸Garcinia acid；Garcinia acid|||(-)-羥基檸檬酸 (2024/8/29)
簡介：(-)-hydroxycitric acid (garcinia acid) (garcinia acid) is the principal acid of fruit rinds of garcinia cambogia. it is a potent and competitive inhibitor of atp citrate lyase. (-)-hydroxycitric acid suppresses fatty acid synthesis, food intake, lipogenesis, and induced weight loss.
Leflunomide來氟米特SU101|||RS-34821|||HWA486|||來氟米特 (2024/8/29)
簡介：leflunomide (hwa486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
Phenoxybenzamine；化合物 T1158LNSC-37448|||A688|||NSC 37448|||NSC37448|||A-688；NSC-37448|||A688|||NSC 37 (2024/8/29)
簡介：phenoxybenzamine is an α-1 adrenergic receptor antagonist. phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after traumatic brain injury.
Hydroxycitric acid tripotassium hydrate三水合鉀檸檬酸檸檬酸鉀一水合物|||三水合鉀檸檬酸|||Potassium citrate monohydrate (2024/8/29)
簡介：hydroxycitric acid tripotassium hydrate (potassium citrate monohydrate) effectively inhibits stones formation and also inhibits hif, and has antioxidation, anti-inflammation, and anti-tumor effects. hydroxycitric acid tripotassium hydrate(potassium citrate monohydrate) (potassium citrate monohydrate) is the major active ingredient of garcinia cambogia and a derivative of citric acid. hydroxycitric acid tripotassium hydrate(potassium citrate monohydrate) competitively inhibits atp citrate lyase w
Hydroxyamine hydrochloride；羥胺鹽酸鹽Hydroxylammonium chloride|||Hydroxylamine hydrochloride；Hydroxylammo (2024/8/29)
簡介：hydroxyamine hydrochloride(hydroxylammonium chloride) is a selective and potent monoamine oxidase (mao) inhibitor with inhibitory effects on platelet aggregation.hydroxyamine hydrochloridee is an intermediate in organic synthesis and can be used to synthesize other active compounds.
Hydroxy ziprasidone；化合物 T11586Hydroxy ziprasidone (2024/8/29)
簡介：hydroxy ziprasidone is an impurity of ziprasidone. ziprasidone, an antipsychotic agent, is a 5-ht and dopamine receptor antagonist.
Hydroxy Itraconazole D8；化合物 T11585R-63373 D8；R-63373 D8 (2024/8/29)
簡介：hydroxy itraconazole d8 is the deuterium-labeled hydroxy itraconazole. hydroxy itraconazole is an active metabolite of itraconazole, which is a triazole antifungal agent.
Hydroxy desmethyl Bosentan；化合物 T11584Ro 64-1056；Ro 64-1056 (2024/8/29)
簡介：hydroxy desmethyl bosentan (ro 64-105) is a bosentan metabolism produced by the cytochrome p450 enzymes cyp2c9 and cyp3a4 in the liver.
HWL-088；化合物 T11583HWL-088 (2024/8/29)
簡介：hwl-088 is a potent free fatty acid receptor 1 (ffa1/gpr40) agonist. hwl-088 significantly improves glucose tolerance in normal and diabetic models.
HSV-TK substrate；化合物 T11582HSV-TK substrate (2024/8/29)
簡介：hsv-tk substrate is a substrate for hsv-tk with antitumor activity. it induces multi-log cytotoxicity in hsv-tk-expressing and bystander cells.
HSR6071；化合物HSR6071HSR6071 (2024/8/29)
簡介：hsr6071 is a novel orally active and potent anti-allergic agent with inhibitory effects on passive cutaneous anaphylaxis. hsr6071 showed anti-asthmatic activity in a rat model of experimental asthma.
Heme Oxygenase-1-IN-1 hydrochloride；化合物 T11580LHO-1-IN-1 hydrochloride；HO-1-IN-1 hydrochloride (2024/8/29)
簡介：ho-1-in-1 hydrochloride is a heme oxygenase 1 (ho-1) inhibitor (ic50: 250 nm).
Heme Oxygenase-1-IN-1；化合物Heme Oxygenase-1-IN-1HO-1-IN-1；HO-1-IN-1 (2024/8/29)
簡介：heme oxygenase-1-in-1 (ho-1-in-1) is a heme oxygenase 1 (ho-1) inhibitor (ic50: 250 nm).
Phenoxybenzamine hydrochloride；鹽酸酚芐明NCI-c01661|||NSC 37448|||Phenoxybenzamine HCl；苯氧苯札明|||NCI-c01661 (2024/8/29)
簡介：phenoxybenzamine hydrochloride (nci-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors whi
HSL-IN-3；化合物HSL-IN-3HSL inhibitor 3|||Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate；HSL inh (2024/8/29)
簡介：hsl-in-3 (hsl inhibitor 3) is a boronic acid derivative that is an inhibitor of hormone-sensitive lipase(hsl).
Encequidar mesylate；化合物Encequidar mesylateHM30181 mesylate|||HM30181A mesylate；HM30181 mesylate|||HM (2024/8/29)
簡介：encequidar mesylate (hm30181a mesylate) is a competitive p-glycoprotein inhibitor.
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